Sandra Knowles
ARTICLES BY THIS AUTHOR
- 7/17/2023
Measures to reduce acetaminophen hepatotoxicity
The FDA mandate to limit the dosage of acetaminophen to 325 mg in tablets that combine acetaminophen and opioid medications significantly reduced cases of hospitalizations and serious liver injury. - 4/10/2023
Evaluating patients for drug-induced liver injury
Drug-induced liver injury can range from asymptomatic liver enzyme elevation, the most common presentation, to acute liver failure. - 4/10/2023
Hormone therapy safety in breast cancer survivors
Use of systemic and vaginal estrogens can help to mitigate unwanted effects of adjuvant endocrine therapy; however, concern has been raised regarding a possible increased risk of breast cancer recurrence. - 12/6/2022
Do psychotropic medications affect COVID-19 risk?
Persons with serious mental illness are particularly vulnerable to COVID-19. - 12/5/2022
Melatonin poisonings increasing in children
Melatonin, an endogenous neurohormone that regulates the sleep-wake cycle, is used in the treatment of insomnia in adults and for primary sleep disorders in children. - 9/19/2022
Tofacitinib: cardiovascular and cancer risks
Janus kinase inhibitors are oral targeted agents used for the treatment of various chronic inflammatory diseases including rheumatoid arthritis, psoriatic arthritis, ulcerative colitis and atopic dermatitis. - 9/19/2022
Stroke risk with antidopaminergic antiemetics
Antipsychotic medications with centrallyacting antidopaminergic properties (e.g., risperidone, haloperidol) have been shown to increase the risk of ischemic stroke, especially in older patients and patients with dementia. - 5/24/2022
Is apixaban preferred over rivaroxaban in AF?
For patients with a higher baseline bleeding risk, apixaban may be a better choice than rivaroxaban. - 5/24/2022
Myocarditis/pericarditis risk with COVID-19 vaccines
Cases of myocarditis/ pericarditis following COVID-19 vaccination have generally occurred more frequently in adolescents and young men (<30 years). - 10/7/2021
Safety and Efficacy of DOACS in CKD/Dialysis
Data are limited on the safety and efficacy of DOACs in patients with CKD
