Sandra Knowles
ARTICLES BY THIS AUTHOR
- 10/23/2025
Amiodarone adverse effects
Amiodarone is an antiarrhythmic drug used to treat various ventricular and atrial tachyarrhythmias. Although it is an effective drug, amiodarone is associated with many different adverse effects, including pulmonary, thyroid, ocular and liver toxicity. - 9/21/2025
Finasteride and suicide ideation
Finasteride, a type 2 5-alpha-reductase inhibitor, is indicated for treatment of benign prostatic hyperplasia and for androgenetic alopecia in men. - 6/26/2025
GLP-1 receptor agonists and pancreatic cancer
This study provides reassuring data that GLP-1 receptor agonists are not associated with an increased risk of pancreatic cancer. - 6/24/2025
Antidepressant-induced weight gain
Antidepressants are commonly used medications, with about 16% of people in Canada using antidepressants in 2023. - 1/20/2025
Adverse drug events in outpatient settings
ADEs in the outpatient setting are common, occuring in approximately 5% of patients. Of these, 22% are considered preventable. - 1/16/2025
Antihypertensives and eczematous dermatitis
Rates of eczematous dermatitis have been increasing among older adults. - 9/26/2024
Pseudoephedrine: risk of PRES/RCVS
The European Pharmacovigilance Risk Assessment Committee reviewed reported cases and post-marketing safety data to evaluate the risks of PRES and RCVS with pseudoephedrine-containing medicines. - 9/23/2024
Do PPIs increase risk for migraine?
Proton pump inhibitors are commonly used medications for the treatment and prevention of gastric acid-related upper gastrointestinal disease. - 6/11/2024
Safety of combining PDE5 inhibitors and nitrates
Some studies have demonstrated lower mortality with phosphodiesterase-5 inhibitor treatment for erectile dysfunction in men with stable coronary artery disease, compared with no treatment. - 6/9/2024
GLP-1 agonists and suicidality
Cases of suicidality have been reported among patients using GLP-1 receptor agonists for diabetes and/or obesity.
