Three new drugs pharmacists and physicians need to know about (plus three new generics)

NEW PRODUCTSAflivuaflibercept solution for intravitreal injection; 2 mg/0.05 mL single-use vials and single-use prefilled syringe, Apotex.INDICATIONS Treatment of neovascular (wet) age-related macular degeneration, visual impairment due to macular edema secondary to central retinal vein occlusion, visual impairment due to macular edema secondary to branch retinal vein occlusion, diabetic macular edema, and myopic choroidal neovascularization.DOSAGE Schedule varies according to indication; consult product monograph for details.comments Biosimilar to Eylea.Okedirisperidone 75 mg or 100 mg powder for extended-release injectable suspension; two-syringe mixing system, including a powder syringe and syringe prefilled with the solvent dimethyl sulfoxide, Bausch Health.INDICATIONS Treatment of schizophrenia in adults.DOSAGE 75 mg or 100 mg every four weeks administered as an intramuscular deltoid or gluteal injection. Establish tolerability with oral risperidone before initiating Okedi. Okedi 75 mg injection every four weeks is similar to oral risperidone 3 mg/day. Okedi 100 mg injection every four weeks is similar to oral risperidone 4 mg/day. Patients who are stable on oral risperidone doses 4 mg/day may not be candidates for Okedi.comments Supplied as a kit containing the solvent liquid prefilled syringe, powder prefilled syringe and two safety needles; a 21G, one-inch safety needle with a green cap for deltoid administration and a 20G, two-inch safety needle with a yellow cap for gluteal administration.Yesafiliaflibercept solution for intravitreal injection; 2 mg/0.05 mL single-use vials, Biocon Biologics (Mississauga, ON).INDICATIONS Treatment of neovascular (wet) age-related macular degeneration,visual impairment due to macular edema secondary to central retinal vein occlusion, visual impairment due to macular edema secondary to branch retinal vein occlusion, diabetic macular edema, and myopic choroidal neovascularization.DOSAGE Schedule varies according to indication; consult product monograph for details.COMMENTS Biosimilar to Eylea.New generics• Arsenic Trioxide for Injection (arsenic trioxide 1 mg/mL solution for injection) 10 mL vials, Marcan. Generic alternative to Trisenox.•Mar-Dienogest (dienogest 2 mg tablets), Marcan. Generic alternative to Visanne.• pms-Sugammadex (sugammadex injection 100 mg/mL); 2 mL and 5 mL single-dose vials, Pharmascience. Generic alternative to Bridion.

Three new drugs pharmacists and physicians need to know about (plus three new generics)

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