Renin-angiotensin system inhibitors, including angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, are established teratogens, whereas the teratogenicity of statins is suspected but uncertain.
Using chronological age alone to implement deprescribing is not appropriate, as many nonfrail older adults would benefit from continued antihypertensive treatment.
The field of cell and gene therapies is a fascinating and complex area of drug development that has led to breakthroughs in the treatment of several types of cancer and some rare genetic disorders.
