Geriatrics

Study shows a blood test can help identify healthy people at high risk for Alzheimer’s disease
That information could be reassuring or terrifying, but for now it’s a potential tool to speed drug development by helping to identify and enroll high-risk people into studies of possible Alzheimer’s treatments or preventive strategies.
New research explains what’s behind these hugely common statin side effects
McMaster researchers say the next step is to block the cause of these side effects without compromising the benefits of the drug.

An experimental Alzheimer’s drug shows promise targeting a different brain protein, new study shows

Tau is one part of a toxic duo fueling Alzheimer’s but prior attempts to develop drugs that can target the protein have failed.
A fatal 10-fold hydromorphone overdose prompts ISMP Canada warning on home palliative care

A patient was prescribed 1 mg of hydromorphone at home. Instead, they received four 10 mg injections. By the time the mistake was caught, it was too late.
What to consider about prescriptions of Lecanemab for early Alzheimer’s

CMAJ authors provide decision-making pathway to help clinicians weigh benefits and risks and engage with patients and caregivers.
NEW DRUG: Kisunla for early Alzheimer’s disease

Get the info you need on this new product, part of our drug news roundup for July.
POP QUIZ: Deprescribing statins

Based on the deprescribing.org evidence-based clinical practice guideline for deprescribing statins in older adults, which statement is FALSE?
How have dietary supplement use patterns changed over a recent 25-year period?

Study evaluates 25-year (1999–2023) trends in dietary supplement use among U.S. adults.
Online therapy developed in Montreal helps seniors sleep better, study finds

The program is based on cognitive behavioural therapy, widely considered the first-line treatment for chronic insomnia.
Seniors should get annual medication reviews in primary care: new guidelines

Canadian guidelines on screening for potentially inappropriate prescribing in seniors has just two recommendations and doesn't include independent reviews by community pharmacists.

Study shows a blood test can help identify healthy people at high risk for Alzheimer’s disease

New research explains what’s behind these hugely common statin side effects

An experimental Alzheimer’s drug shows promise targeting a different brain protein, new study shows

A fatal 10-fold hydromorphone overdose prompts ISMP Canada warning on home palliative care

What to consider about prescriptions of Lecanemab for early Alzheimer’s

NEW DRUG: Kisunla for early Alzheimer’s disease

POP QUIZ: Deprescribing statins

How have dietary supplement use patterns changed over a recent 25-year period?

Online therapy developed in Montreal helps seniors sleep better, study finds

Seniors should get annual medication reviews in primary care: new guidelines