Drugs

Two double-blind, randomized controlled trials show positive effects of tirzepatide, with or without concomitant use of positive airway pressure therapy.

Canadian patients wait a very long time, much longer than in other developed countries, before being able to access new treatments, notes the Conference Board of Canada.

Prior failure of other migraine preventive treatments should not be required before using CGRP-targeting therapies for migraine prevention.

The presence of certain proteins could act as an alarm signal announcing the disease before it reaches the acute phase.

Canadian Cardiovascular Society issues guidance on management, including use of the new cardiac myosin inhibitor, mavacamten, for symptomatic disease.

An outside expert cautioned in an editorial that more research will be needed to tell if the drug can be used as ‘a sole treatment’ for obstructive sleep apnea.

Insulin icodec, which will be sold under the brand name Awiqli, is the first once-a-week basal insulin injection in the world and it will be available across the country starting June 30.

Some studies have demonstrated lower mortality with phospho­diesterase-5 inhibitor treatment for erectile dysfunction in men with stable coronary artery disease, compared with no treatment.