Drugs

Food for thought: Uncovering the complexities of drug–nutrition interactions
Vulnerability to drug-induced nutritional deficiencies is greatest in older adults, patients taking multiple medications and those with chronic illness, multiple co-morbidities, or marginal or inadequate nutrition.
Zuranolone for postpartum depression: Hope, hype or both?
Early studies of zuranolone suggest PPD symptom improvement can be observed as early as three days after starting the treatment. This is an unusually rapid response to an antidepressant medication, which usually take effect over several weeks.

U.S. approves updated COVID vaccines to rev up protection this fall

The Food and Drug Administration decision opens the newest shots from Moderna and Pfizer and its partner BioNTech to most Americans even if they’ve never had a coronavirus vaccination.
Naloxone kits across Canada should have both nasal spray and injection options: panel

The new guidance, led by the BC Centre for Disease Control, aims to standardize take-home naloxone kits that are distributed through various sites, including pharmacies, community groups and emergency departments, to anyone who could respond to an overdose.
POP QUIZ: Desmopressin for bedwetting

All the following statements about use of desmopressin for monosymptomatic enuresis (bedwetting without any daytime lower urinary tract symptoms) in children are true, EXCEPT for . . .
Acetylcysteine infusion overdoses lead to multiple deaths

The Institute for Safe Medication Practices Canada has found key similarities in all cases that led to the overdoses.
Infant antibiotics use and disrupted gut microbiome linked to childhood allergies, asthma and eczema, researchers say

The risk of developing at least one of the major allergies more than doubled by age five for kids who had been prescribed antibiotics before their first birthday.
New agent lowers Lp(a) levels

While the Canadian Cardiovascular Society’s lipid guidelines recommend a once in a lifetime testing of Lp(a), there are no approved agents for lowering Lp(a) levels.
Nasal discharge colour a poor guide for antibiotic use in acute sinusitis

Testing for pathogens could reduce antibiotic use 28%.
Prevnar 20 now indicated for immunization of infants, children and adolescents

The routine vaccination schedule for prevention of invasive pneumococcal disease is a three-dose primary series followed by a toddler booster dose.

Food for thought: Uncovering the complexities of drug–nutrition interactions

Zuranolone for postpartum depression: Hope, hype or both?

U.S. approves updated COVID vaccines to rev up protection this fall

Naloxone kits across Canada should have both nasal spray and injection options: panel

POP QUIZ: Desmopressin for bedwetting

Acetylcysteine infusion overdoses lead to multiple deaths

Infant antibiotics use and disrupted gut microbiome linked to childhood allergies, asthma and eczema, researchers say

New agent lowers Lp(a) levels

Nasal discharge colour a poor guide for antibiotic use in acute sinusitis

Prevnar 20 now indicated for immunization of infants, children and adolescents